Stochastic gene expression and chromosome interactions in protecting the human active X from silencing by XIST
Mammals use Pop Vinyl X chromosome inactivation to compensate for the sex difference in numbers of X chromosomes.A relatively unexplored question is how the active X is protected from inactivation by its own XIST gene, the long non-coding RNA, which initiates silence of the inactive X.Previous studies of autosomal duplications show that human chrom